As for using ALA topically, we have to say that its role and effects seem to be less direct than with LA
Moreover, ferroptosis may not only play a direct role in AT, but also indirectly promote the development of obesity through the inflammatory response and insulin resistance caused by liver autonomic and immunomodulatory disorders( Figure 4 )
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Yu S, Chen Y, Chen S, Ye N, Li Y, Sun Y (2018) Klotho inhibits proliferation and migration of Angiotensin II-induced vascular smooth muscle cells (VSMCs) by modulating NF-B p65, Akt, and Extracellular Signal Regulated Kinase (ERK) signaling activities